Neoadjuvant-intensified treatment for rectal cancer: Time to change?
نویسندگان
چکیده
منابع مشابه
Intensified neoadjuvant radio-chemotherapy for locally advanced rectal cancer: mono-istitutional experience and long-term results
Background: Purpose: The purpose of our study is to demonstrate that intensified neoadjuvant chemo-radiotherapy (CRT) treatment in locally advanced rectal cancer (LARC), aimed at further enhancing the complete pathological response and local disease control, is feasible and well tolerated. Materials and Methods: From January 2011 to December 2015, 62 patients (women 21, men 41, mean age 61,5, ...
متن کاملIntensified neoadjuvant radiochemotherapy for rectal cancer enhances surgical complications
BACKGROUND Neoadjuvant radiochemotherapy has proven superior to adjuvant treatment in reducing the rate of local recurrence without impairing cancer related survival or the incidence of distant metastases. The present study aimed at addressing the effects of an intensified protocol of neoadjuvant treatment on the development of postoperative complications. METHODS A total of 387 patients unde...
متن کاملComparison between intensified neoadjuvant treatment and standard preoperative chemoradiation for rectal cancer.
OBJECTIVES The aim of the current study was to compare a neoadjuvant regimen containing oxaliplatin with standard preoperative treatment for rectal cancer. METHODS From December 2006 to December 2007, 20 patients with rectal cancer were treated at our Institution with the weekly addition of oxaliplatin (50 mg/m(2)) to radiotherapy (50.4-54.0 Gy in 28-30 daily fractions) and continuous infusio...
متن کاملNew drug in neoadjuvant chemoradiation for rectal cancer
Background: In recent years, neoadjuvant chemoradiation and subsequent surgical resection with total mesorectal excision has been shown to increase local control with decreased toxicity. Neoadjuvant chemoradiotherapy is the standard treatment for locally advanced rectal cancer. In this study we evaluated the efficacy a cox-2 inhibitor on pathologic response, sphincter preservation and acute tox...
متن کاملAuthor's response to reviews Title: Intensified Neoadjuvant Radiochemotherapy for Rectal Cancer Enhances Surgical Complications Authors:
Leif Schiffmann ([email protected]) Nicole Wedermann ([email protected]) Michael Gock ([email protected]) Friedrich Prall ([email protected]) Gunther Klautke ([email protected]) Rainer Fietkau ([email protected]) Bettina Rau ([email protected]) Ernst Klar ([email protected]...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: World Journal of Gastroenterology
سال: 2013
ISSN: 1007-9327
DOI: 10.3748/wjg.v19.i20.3052